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Peptide record

TPDB15732

Antibacterial Antifungal Toxicity modified_plain modified
11 amino acids
Basic Information
3D PDB MODEL
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TPDB15732
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia CAFPdb
modified_plain
Yes
A 11-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, and CAFPdb, with an available 3D structural model.
Modified, details unspecified
Sequence
XGLXGGLXKIL
Physicochemical Analysis
C36H67N9O9
ARNDCEQHMFPSTWYV
GL
769.98
10.10
1
0
4
+1
-0.97
0.982
141.82
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
3
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 3 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C36H67N9O9
769.98
10.10
+1
-0.97
0.982
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
8 µM
Hemolytic Cytotoxic
0% Hemolysis | 8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The peculiar N- and (-termini of trichogin GA IV are needed for membrane interaction and human cell death induction at doses lacking antibiotic activity. | Biochim Biophys Acta | 2015
Evidence 2 Activity

Activity

5% Hemolysis
Toxicity
16 µM
Hemolytic Cytotoxic
5% Hemolysis | 16 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The peculiar N- and (-termini of trichogin GA IV are needed for membrane interaction and human cell death induction at doses lacking antibiotic activity. | Biochim Biophys Acta | 2015
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochim Biophys Acta. 2015 Jan 1848(1 Pt A):134-53.