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Peptide record

TPDB15706

Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB15706
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
KKLFKKILRYL
Physicochemical Analysis
C72H124N18O13
ANDCEQGHMPSTWV
K
1449.89
11.04
5
0
6
+5
0.71
-0.245
141.82
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
102.77
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
4
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
11
C72H124N18O13
1449.89
11.04
+5
0.71
-0.245
Evidence Records 1 records
Evidence 1 Activity

Activity

31% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
31% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
An Amphipathic Undecapeptide With All d-Amino Acids Shows Promising Activity Against Colistin-Resistant Strains of Acinetobacter Baumannii and a Dual Mode of Action | Antimicrob Agents Chemother | 2015