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Peptide record

TPDB15703

Antibacterial Anticancer Hemolysis Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB15703
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia PD_Hemolysis
standard
No
A 7-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from dbAMP, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
ELLSRVD
Physicochemical Analysis
C35H62N10O13
ANCQGHIKMFPTWY
L
830.94
4.07
1
2
3
-1
3.14
-0.071
152.86
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
1
E
0
Q
0
G
0
H
0
I
2
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
7
C35H62N10O13
830.94
4.07
-1
3.14
-0.071
Evidence Records 7 records
Evidence 1 Activity

Activity

18% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
18% Hemolysis | 50 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
A Biosurfactant-Inspired Heptapeptide with Improved Specificity to Kill MRSA. | Angew Chem Int Ed Engl | 2017
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 100 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
A Biosurfactant-Inspired Heptapeptide with Improved Specificity to Kill MRSA. | Angew Chem Int Ed Engl | 2017
Evidence 3 Activity

Activity

50% Cell death
Toxicity
92.9 µg/mL
Cytotoxic
50% Cell death | 92.9 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
A Biosurfactant-Inspired Heptapeptide with Improved Specificity to Kill MRSA. | Angew Chem Int Ed Engl | 2017
Evidence 4 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
A Biosurfactant-Inspired Heptapeptide with Improved Specificity to Kill MRSA. | Angew Chem Int Ed Engl | 2017
Evidence 5 Activity

Activity

<5% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 100 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
A Biosurfactant-Inspired Heptapeptide with Improved Specificity to Kill MRSA. | Angew Chem Int Ed Engl | 2017
Evidence 6 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Chem Int Ed Engl. 2017 Feb 1 56(6):1486-1490.
Evidence 7 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis