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Peptide record

TPDB15699

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB15699
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
FRQWYRRVRRYWQRF
Physicochemical Analysis
C109H155N37O20
ANDCEGHILKMPST
R
2303.67
12.40
6
0
7
+6
-1.75
-1.907
19.33
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
13980
606.86
4
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
2
Q
0
G
0
H
0
I
0
L
0
K
0
M
2
F
0
P
0
S
0
T
2
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 2 P: 0 S: 0 T: 0 W: 2 Y: 2 V: 1
Chemical Descriptors
15
C109H155N37O20
2303.67
12.40
+6
-1.75
-1.907
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
5% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Non-perfectly Amphipathic α-Helical Structure Containing the XXYXX Sequence Improves the Biological Activity of Bovine αs2-Casein Antimicrobial Peptides. | J Agric Food Chem | 2020
Evidence 2 Activity

Activity

28.9% Hemolysis
Toxicity
256 µM
Cytotoxic
28.9% Hemolysis | 256 | µM | target cell: Human endothelial hybrid cells Ea.hy 926

Target

Human endothelial hybrid cells Ea.hy 926

Source & Reference

NA
DBAASP
Non-perfectly Amphipathic α-Helical Structure Containing the XXYXX Sequence Improves the Biological Activity of Bovine αs2-Casein Antimicrobial Peptides. | J Agric Food Chem | 2020