Back to search

Peptide record

TPDB15698

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB15698
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
FKQFYRRVRRYFQKF
Physicochemical Analysis
C105H153N31O20
ANDCEGHILMPSTW
RF
2169.57
11.98
6
0
7
+6
0.05
-1.333
19.33
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
2980
137.35
4
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
2
Q
0
G
0
H
0
I
0
L
2
K
0
M
4
F
0
P
0
S
0
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 0 L: 0 K: 2 M: 0 F: 4 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 1
Chemical Descriptors
15
C105H153N31O20
2169.57
11.98
+6
0.05
-1.333
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
5% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Non-perfectly Amphipathic α-Helical Structure Containing the XXYXX Sequence Improves the Biological Activity of Bovine αs2-Casein Antimicrobial Peptides. | J Agric Food Chem | 2020
Evidence 2 Activity

Activity

18.39% Killing
Toxicity
256 µM
Cytotoxic
18.39% Killing | 256 | µM | target cell: Human endothelial hybrid cells Ea.hy 926

Target

Human endothelial hybrid cells Ea.hy 926

Source & Reference

NA
DBAASP
Non-perfectly Amphipathic α-Helical Structure Containing the XXYXX Sequence Improves the Biological Activity of Bovine αs2-Casein Antimicrobial Peptides. | J Agric Food Chem | 2020