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Peptide record

TPDB15697

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB15697
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
FWQVIKKVKKIVQWF
Physicochemical Analysis
C101H153N23O18
ARNDCEGHLMPSTY
K
1977.47
11.00
4
0
9
+4
-1.25
0.187
110.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
556.27
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
2
Q
0
G
0
H
2
I
0
L
4
K
0
M
2
F
0
P
0
S
0
T
2
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 2 L: 0 K: 4 M: 0 F: 2 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 3
Chemical Descriptors
15
C101H153N23O18
1977.47
11.00
+4
-1.25
0.187
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
5% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Non-perfectly Amphipathic α-Helical Structure Containing the XXYXX Sequence Improves the Biological Activity of Bovine αs2-Casein Antimicrobial Peptides. | J Agric Food Chem | 2020
Evidence 2 Activity

Activity

16.49% Killing
Toxicity
256 µM
Cytotoxic
16.49% Killing | 256 | µM | target cell: Human endothelial hybrid cells Ea.hy 926

Target

Human endothelial hybrid cells Ea.hy 926

Source & Reference

NA
DBAASP
Non-perfectly Amphipathic α-Helical Structure Containing the XXYXX Sequence Improves the Biological Activity of Bovine αs2-Casein Antimicrobial Peptides. | J Agric Food Chem | 2020