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Peptide record

TPDB15671

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB15671
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
RRGWARRLLRAFAFGRR
Physicochemical Analysis
C96H157N39O18
NDCEQHIKMPSTYV
R
2145.55
13.18
7
0
8
+7
-0.05
-0.859
63.53
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
256.34
0
Residue Composition
number
3
A
7
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
2
L
0
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 7 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 2 K: 0 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
17
C96H157N39O18
2145.55
13.18
+7
-0.05
-0.859
Evidence Records 1 records
Evidence 1 Activity

Activity

15% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
15% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthetic molecular evolution of host cell-compatible, antimicrobial peptides effective against drug-resistant, biofilm-forming bacteria. | Proc Natl Acad Sci U S A | 2020