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Peptide record

TPDB15662

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB15662
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
RRGWAFRRALAYGRR
Physicochemical Analysis
C84H134N34O17
NDCEQHIKMPSTV
R
1892.21
12.70
6
0
7
+6
-0.11
-1.200
46.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
6990
369.41
1
Residue Composition
number
3
A
6
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 3 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
15
C84H134N34O17
1892.21
12.70
+6
-0.11
-1.200
Evidence Records 1 records
Evidence 1 Activity

Activity

1% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
1% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthetic molecular evolution of host cell-compatible, antimicrobial peptides effective against drug-resistant, biofilm-forming bacteria. | Proc Natl Acad Sci U S A | 2020