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Peptide record

TPDB15657

Antibacterial Anticancer Antifungal Toxicity standard
40 amino acids
Basic Information
3D PDB MODEL
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TPDB15657
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia CAFPdb
standard
No
A 40-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, and CAFPdb, with an available 3D structural model.
Sequence
RVQGRWKVRASFFKGGGGSGFAWNVCVYRNGVRVCHRRAN
Physicochemical Analysis
C200H309N71O48S2
DEILMPT
RG
4540.22
12.29
10
0
15
+9
2.18
-0.500
51.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
12615
277.85
9
Residue Composition
number
3
A
7
R
3
N
0
D
2
C
0
E
1
Q
7
G
1
H
0
I
0
L
2
K
0
M
3
F
0
P
2
S
0
T
2
W
1
Y
6
V
Amino Acid Distribution
A: 3 R: 7 N: 3 D: 0 C: 2 E: 0 Q: 1 G: 7 H: 1 I: 0 L: 0 K: 2 M: 0 F: 3 P: 0 S: 2 T: 0 W: 2 Y: 1 V: 6
Chemical Descriptors
40
C200H309N71O48S2
4540.22
12.29
+9
2.18
-0.500
Evidence Records 1 records
Evidence 1 Activity

Activity

0.026% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
0.026% Hemolysis | 256 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Development of chimeric peptides to facilitate the neutralisation of lipopolysaccharides during bactericidal targeting of multidrug-resistant Escherichia coli. | Commun Biol | 2020