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Peptide record

TPDB15656

Antibacterial Anticancer Antifungal Toxicity standard
45 amino acids
Basic Information
3D PDB MODEL
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TPDB15656
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia CAFPdb
standard
No
A 45-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, and CAFPdb, with an available 3D structural model.
Sequence
RVQGRWKVRASFFKEAAAKEAAAKGFAWNVCVYRNGVRVCHRRAN
Physicochemical Analysis
C229H360N78O56S2
DILMPT
A
5165.99
11.74
12
2
21
+9
7.01
-0.480
58.67
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
12615
244.19
8
Residue Composition
number
9
A
7
R
3
N
0
D
2
C
2
E
1
Q
3
G
1
H
0
I
0
L
4
K
0
M
3
F
0
P
1
S
0
T
2
W
1
Y
6
V
Amino Acid Distribution
A: 9 R: 7 N: 3 D: 0 C: 2 E: 2 Q: 1 G: 3 H: 1 I: 0 L: 0 K: 4 M: 0 F: 3 P: 0 S: 1 T: 0 W: 2 Y: 1 V: 6
Chemical Descriptors
45
C229H360N78O56S2
5165.99
11.74
+9
7.01
-0.480
Evidence Records 1 records
Evidence 1 Activity

Activity

1.2% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
1.2% Hemolysis | 256 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Development of chimeric peptides to facilitate the neutralisation of lipopolysaccharides during bactericidal targeting of multidrug-resistant Escherichia coli. | Commun Biol | 2020