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Peptide record

TPDB15655

Antibacterial Antifungal Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB15655
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia CAFPdb ToxinPred 3.0
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
KRFKKFWKKIKNSVKKRAKKFFRKPRVIAVSIPF
Physicochemical Analysis
C205H337N59O38
DCEQGHLMTY
K
4236.30
12.90
15
0
14
+15
7.15
-0.776
65.88
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
129.83
3
Residue Composition
number
2
A
4
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
0
L
11
K
0
M
5
F
2
P
2
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 4 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 0 K: 11 M: 0 F: 5 P: 2 S: 2 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
34
C205H337N59O38
4236.30
12.90
+15
7.15
-0.776
Evidence Records 3 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
<50 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | <50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of a Novel Cathelicidin from the Deinagkistrodon acutus Genome with Antibacterial Activity by Multiple Mechanisms. | Toxins (Basel) | 2020
Evidence 2 Activity

Activity

11% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
11% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of a Novel Cathelicidin from the Deinagkistrodon acutus Genome with Antibacterial Activity by Multiple Mechanisms. | Toxins (Basel) | 2020
Evidence 3 Activity

Activity

17% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
17% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of a Novel Cathelicidin from the Deinagkistrodon acutus Genome with Antibacterial Activity by Multiple Mechanisms. | Toxins (Basel) | 2020