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Peptide record

TPDB15654

Antibacterial Anticancer Antifungal Toxicity modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
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TPDB15654
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia CAFPdb
modified_plain
Yes
A 14-aa modified multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, and CAFPdb, with an available 3D structural model.
Modified, details unspecified
Sequence
XRLFKKLLKYLRKX
Physicochemical Analysis
C78H136N22O14
ANDCEQGHIMPSTWV
LK
1606.08
11.65
6
0
6
+6
1.27
-0.564
111.43
Mammalian: Yeast: E.coli:
1490
92.77
1
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
4
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C78H136N22O14
1606.08
11.65
+6
1.27
-0.564
Evidence Records 6 records
Evidence 1 Activity

Activity

19.02±0.08% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
19.02±0.08% Hemolysis | 32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics. | Front Microbiol | 2020
Evidence 2 Activity

Activity

55.99±3.75% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
55.99±3.75% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics. | Front Microbiol | 2020
Evidence 3 Activity

Activity

95.99±2.1% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
95.99±2.1% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics. | Front Microbiol | 2020
Evidence 4 Activity

Activity

22.52±1.07% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
22.52±1.07% Hemolysis | 32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics. | Front Microbiol | 2020
Evidence 5 Activity

Activity

56.82±2.62% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
56.82±2.62% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics. | Front Microbiol | 2020
Evidence 6 Activity

Activity

95.02±1.84% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
95.02±1.84% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics. | Front Microbiol | 2020