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Peptide record

TPDB15621

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB15621
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
KKWVPLKKIANIL
Physicochemical Analysis
C76H131N19O15
RDCEQGHMFSTY
K
1550.99
11.00
4
0
7
+4
1.14
0.077
150.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
354.61
1
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
2
L
4
K
0
M
0
F
1
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 2 K: 4 M: 0 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
13
C76H131N19O15
1550.99
11.00
+4
1.14
0.077
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
<5% Hemolysis | 256 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
In Vitro & In Vivo Studies on Identifying and Designing Temporin-1CEh from the Skin Secretion of Rana chensinensis as the Optimised Antibacterial Prototype Drug | Pharmaceutics | 2022