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Peptide record

TPDB15618

Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB15618
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
FVDLKKIANII
Physicochemical Analysis
C61H104N14O15
RCEQGHMPSTWY
I
1273.58
9.88
2
1
7
+1
0.91
1.027
177.27
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
0
R
1
N
1
D
0
C
0
E
0
Q
0
G
0
H
3
I
1
L
2
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 1 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
11
C61H104N14O15
1273.58
9.88
+1
0.91
1.027
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
<5% Hemolysis | 256 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
In Vitro & In Vivo Studies on Identifying and Designing Temporin-1CEh from the Skin Secretion of Rana chensinensis as the Optimised Antibacterial Prototype Drug | Pharmaceutics | 2022