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Peptide record

TPDB15581

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB15581
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
RGGRLCYARRRFAVCVGR
Physicochemical Analysis
C88H150N36O20S2
NDEQHIKMPSTW
R
2096.51
12.10
6
0
7
+6
1.58
-0.328
65.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1615
77.03
3
Residue Composition
number
2
A
6
R
0
N
0
D
2
C
0
E
0
Q
3
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 6 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
18
C88H150N36O20S2
2096.51
12.10
+6
1.58
-0.328
Evidence Records 1 records
Evidence 1 Activity

Activity

15% Hemolysis
Toxicity
80 µM
Hemolytic Cytotoxic
15% Hemolysis | 80 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evaluation of the inactivation of infectious Herpes simplex virus by host-defense peptides. | Eur J Clin Microbiol Infect Dis | 2000