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Peptide record

TPDB15566

Antibacterial Anticancer Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB15566
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
FKGLAKLLKIGLKALAKVIQ
Physicochemical Analysis
C104H186N26O22
RNDCEHMPSTWY
LK
2152.78
11.12
5
0
12
+5
0.56
0.830
166.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
1
Q
2
G
0
H
2
I
5
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 2 L: 5 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C104H186N26O22
2152.78
11.12
+5
0.56
0.830
Evidence Records 3 records
Evidence 1 Activity

Activity

75% Cytotoxicity
Toxicity
2 µM
Cytotoxic
75% Cytotoxicity | 2 | µM | target cell: Human bronchial epithelial cells BEAS-2B

Target

Human bronchial epithelial cells BEAS-2B

Source & Reference

NA
DBAASP
Designing a Novel Functional Peptide With Dual Antimicrobial and Anti-inflammatory Activities via in Silico Methods. | Front Immunol | 2022
Evidence 2 Activity

Activity

55% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
55% Hemolysis | 50 | µM | target cell: Bovine erythrocytes

Target

Bovine erythrocytes

Source & Reference

NA
DBAASP
Designing a Novel Functional Peptide With Dual Antimicrobial and Anti-inflammatory Activities via in Silico Methods. | Front Immunol | 2022
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Front Immunol. 2022 Apr 1 13:821070.