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Peptide record

TPDB15553

Antibacterial Toxicity modified_plain modified
7 amino acids
Basic Information
3D PDB MODEL
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TPDB15553
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
modified_plain
Yes
A 7-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
LXWLXXL
Physicochemical Analysis
C29H45N5O5
ARNDCEQGHIKMFPSTYV
L
543.71
6.02
0
0
4
-0
-3.53
1.500
167.14
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
1011.57
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
3
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 3 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
7
C29H45N5O5
543.71
6.02
-0
-3.53
1.500
Evidence Records 2 records
Evidence 1 Activity

Activity

8% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
8% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Delineating the Mechanism of Action of a Protease Resistant and Salt Tolerant Synthetic Antimicrobial Peptide against Pseudomonas aeruginosa. | ACS Omega | 2022
Evidence 2 Activity

Activity

LC50
Toxicity
>300 µM
Cytotoxic
LC50 | >300 | µM | target cell: Human normal embryonic lung cells L132

Target

Human normal embryonic lung cells L132

Source & Reference

NA
DBAASP
Delineating the Mechanism of Action of a Protease Resistant and Salt Tolerant Synthetic Antimicrobial Peptide against Pseudomonas aeruginosa. | ACS Omega | 2022