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Peptide record

TPDB15542

Antibacterial Anticancer Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB15542
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
SYEKKINRHFKILKKNLKKK
Physicochemical Analysis
C118H203N35O27
ADCQGMPTWV
K
2544.13
11.01
10
1
6
+8
8.87
-1.605
78.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
1490
58.57
4
Residue Composition
number
0
A
1
R
2
N
0
D
0
C
1
E
0
Q
0
G
1
H
2
I
2
L
8
K
0
M
1
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 1 I: 2 L: 2 K: 8 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
20
C118H203N35O27
2544.13
11.01
+8
8.87
-1.605
Evidence Records 4 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | 200 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
A Novel Antimicrobial Peptide Derived from Bony Fish IFN1 Exerts Potent Antimicrobial and Anti-Inflammatory Activity in Mammals | Microbiol Spectr | 2022
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
A Novel Antimicrobial Peptide Derived from Bony Fish IFN1 Exerts Potent Antimicrobial and Anti-Inflammatory Activity in Mammals | Microbiol Spectr | 2022
Evidence 3 Activity

Activity

10% Killing
Toxicity
256 µg/mL
Cytotoxic
10% Killing | 256 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
A Novel Antimicrobial Peptide Derived from Bony Fish IFN1 Exerts Potent Antimicrobial and Anti-Inflammatory Activity in Mammals | Microbiol Spectr | 2022
Evidence 4 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Microbiol Spectr. 2022 Apr 27 10(2):e0201321.