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Peptide record

TPDB15513

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB15513
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
RGTCYNRVGLIIRNFSKLKGKKV
Physicochemical Analysis
C118H204N38O29S1
ADEQHMPW
K
2651.22
11.55
7
0
8
+7
3.62
-0.426
93.04
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
56.20
6
Residue Composition
number
0
A
3
R
2
N
0
D
1
C
0
E
0
Q
3
G
0
H
2
I
2
L
4
K
0
M
1
F
0
P
1
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 2 D: 0 C: 1 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 2 K: 4 M: 0 F: 1 P: 0 S: 1 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
23
C118H204N38O29S1
2651.22
11.55
+7
3.62
-0.426
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Inhibited the growth of S. aureus (17%), B. subtilis (87%), E. coli (81%), and P. aeruginosa (73%) at 60 uM. Sequence provided by Dr. Jun Wang. Reg. 3/2022
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
261.18 µM
Hemolytic Cytotoxic
50% Hemolysis | 261.18 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of antimicrobial peptides from the human gut microbiome using deep learning. | Nat Biotechnol | 2022