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Peptide record

TPDB15509

Antibacterial Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB15509
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 29-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
SVIWRKLFFIFIKRSGNWIKKVEKRQNLL
Physicochemical Analysis
C175H280N48O37
ADCHMPTY
K
3648.45
12.17
8
1
14
+7
1.22
-0.159
114.14
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
11000
301.50
5
Residue Composition
number
0
A
3
R
2
N
0
D
0
C
1
E
1
Q
1
G
0
H
4
I
3
L
5
K
0
M
3
F
0
P
2
S
0
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 2 D: 0 C: 0 E: 1 Q: 1 G: 1 H: 0 I: 4 L: 3 K: 5 M: 0 F: 3 P: 0 S: 2 T: 0 W: 2 Y: 0 V: 2
Chemical Descriptors
29
C175H280N48O37
3648.45
12.17
+7
1.22
-0.159
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
10.51 µM
Hemolytic Cytotoxic
50% Hemolysis | 10.51 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of antimicrobial peptides from the human gut microbiome using deep learning. | Nat Biotechnol | 2022