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Peptide record

TPDB15490

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB15490
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
FLALALIPKAIAKLK
Physicochemical Analysis
C80H140N18O16
RNDCEQGHMSTWYV
AL
1610.10
10.84
3
0
11
+3
-1.25
1.393
182.67
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
4
L
3
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 4 K: 3 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C80H140N18O16
1610.10
10.84
+3
-1.25
1.393
Evidence Records 2 records
Evidence 1 Activity

Activity

7% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
7% Hemolysis | 64 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Kassporin-KS1: A Novel Pentadecapeptide from the Skin Secretion of Kassina senegalensis: Studies on the Structure-Activity Relationships of Site-Specific "Glycine-Lysine" Motif Insertions | Antibiotics (Basel) | 2022
Evidence 2 Activity

Activity

25% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
25% Hemolysis | 256 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Kassporin-KS1: A Novel Pentadecapeptide from the Skin Secretion of Kassina senegalensis: Studies on the Structure-Activity Relationships of Site-Specific "Glycine-Lysine" Motif Insertions | Antibiotics (Basel) | 2022