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Peptide record

TPDB15488

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB15488
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
FLAGKLIQEAIAKLK
Physicochemical Analysis
C78H135N19O19
RNDCHMPSTWYV
ALK
1643.05
10.32
3
1
9
+2
1.64
0.633
150.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
1
E
1
Q
1
G
0
H
2
I
3
L
3
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 1 H: 0 I: 2 L: 3 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C78H135N19O19
1643.05
10.32
+2
1.64
0.633
Evidence Records 1 records
Evidence 1 Activity

Activity

7% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
7% Hemolysis | 256 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Kassporin-KS1: A Novel Pentadecapeptide from the Skin Secretion of Kassina senegalensis: Studies on the Structure-Activity Relationships of Site-Specific "Glycine-Lysine" Motif Insertions | Antibiotics (Basel) | 2022