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Peptide record

TPDB15425

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB15425
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
KAIAAFAAKLFI
Physicochemical Analysis
C63H102N14O13
RNDCEQGHMPSTWYV
A
1263.59
10.60
2
0
10
+2
-2.31
1.633
139.17
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
5
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
2
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 2 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C63H102N14O13
1263.59
10.60
+2
-2.31
1.633
Evidence Records 1 records
Evidence 1 Activity

Activity

7% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
7% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
In Silico and In Vitro Structure-Activity Relationship of Mastoparan and Its Analogs. | Molecules | 2022