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Peptide record

TPDB15417

Antibacterial Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB15417
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 27-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
GLMDTVKNAAKNLAGQLLDKIKCKITG
Physicochemical Analysis
C123H219N35O37S2
REHFPSWY
K
2844.42
10.05
5
2
11
+3
5.37
-0.052
108.52
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
6
Residue Composition
number
3
A
0
R
2
N
2
D
1
C
0
E
1
Q
3
G
0
H
2
I
4
L
5
K
1
M
0
F
0
P
0
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 2 C: 1 E: 0 Q: 1 G: 3 H: 0 I: 2 L: 4 K: 5 M: 1 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
27
C123H219N35O37S2
2844.42
10.05
+3
5.37
-0.052
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ab initio Designed Antimicrobial Peptides Against Gram-Negative Bacteria | Front Microbiol | 2021