Peptide record

TPDB15395

Antibacterial Toxicity standard
44 amino acids
Basic Information
3D PDB MODEL
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TPDB15395
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 44-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
DKLIGSCVWGAVNYTSDCNAECKRRGYKGGHCGSFANVNCWCET
Physicochemical Analysis
C202H305N61O64S6
QMP
CG
4804.37
7.63
6
4
13
+1
5.14
-0.418
44.32
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
14355
298.79
17
Residue Composition
number
3
A
2
R
4
N
2
D
6
C
2
E
0
Q
6
G
1
H
1
I
1
L
3
K
0
M
1
F
0
P
3
S
2
T
2
W
2
Y
3
V
Amino Acid Distribution
A: 3 R: 2 N: 4 D: 2 C: 6 E: 2 Q: 0 G: 6 H: 1 I: 1 L: 1 K: 3 M: 0 F: 1 P: 0 S: 3 T: 2 W: 2 Y: 2 V: 3
Chemical Descriptors
44
C202H305N61O64S6
4804.37
7.63
+1
5.14
-0.418
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
<10% Hemolysis | 64 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Identification and Characterization of Antimicrobial Peptides From Butterflies: An Integrated Bioinformatics and Experimental Study. | Front Microbiol | 2021
Evidence 2 Activity

Activity

<10% Cytotoxicity
Toxicity
64 µM
Cytotoxic
<10% Cytotoxicity | 64 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Identification and Characterization of Antimicrobial Peptides From Butterflies: An Integrated Bioinformatics and Experimental Study. | Front Microbiol | 2021