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Peptide record

TPDB15366

Antibacterial Toxicity modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB15366
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP DRAMP Peptipedia
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP, DRAMP, and Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GFRSILKKVSPKVXAHXK
Physicochemical Analysis
C83H143N25O19
NDCEQMTWY
K
1795.20
11.80
6
0
6
+5
4.42
-0.311
81.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
1
L
4
K
0
M
1
F
1
P
2
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 1 K: 4 M: 0 F: 1 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
18
C83H143N25O19
1795.20
11.80
+5
4.42
-0.311
Evidence Records 2 records
Evidence 1 Activity

Activity

LC50
Toxicity
11 µM
Hemolytic
Hemolytic_activity: [Ref.22526241]LC50=11 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Amino Acids. 2012 Nov 43(5):2047-58.
Evidence 2 Activity

Activity

LC50
Toxicity
20 µM
Hemolytic
Hemolytic_activity: [Ref.22526241]LC50=20 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Amino Acids. 2012 Nov 43(5):2047-58.