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Peptide record

TPDB15336

P6 Antibacterial Anticancer standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB15336
P6
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
dbAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF
standard
No
A 19-aa standard natural multi-activity (Antibacterial and Anticancer) peptide sequence curated from dbAMP, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
KWKLFKKIGIGKFKLAKKF-NH2
Physicochemical Analysis
C117H190N28O20
RNDCEQHMPSTYV
K
2308.97
11.36
8
0
9
+8
0.79
-0.321
87.37
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
238.20
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
2
L
8
K
0
M
3
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 2 K: 8 M: 0 F: 3 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
19
C117H190N28O20
2308.97
11.36
+8
0.79
-0.321
Amidation
L
Linear
Free
Antibacterial
Ceropin A-Magainin 2
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50=1.7 µM
Anticancer
1.7 µM

Target

Lung Cancer
NCI-H69
Lung

Assay & Model

MTT/MTS assay
72-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1997

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50=2 µM
Anticancer
2 µM

Target

Lung Cancer
NCI-H128
Lung

Assay & Model

MTT/MTS assay
72-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1997
Evidence 3 Activity

Activity

IC50
IC50=3.1 µM
Anticancer
3.1 µM

Target

Lung Cancer
NCI-H146
Lung

Assay & Model

MTT/MTS assay
72-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1997