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Peptide record

TPDB15335

P1 Antibacterial Anticancer modified_plain modified
20 amino acids
Basic Information
3D PDB MODEL
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Standard-residue backbone model; source-recorded chemical modifications are not verified in these coordinates.

TPDB15335
P1
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
dbAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF
modified_plain
Yes
A 20-aa modified multi-activity (Antibacterial and Anticancer) peptide sequence curated from dbAMP, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
KWKLFKKIGIGAVLKVLKKG-NH2
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
20 reviewed residue count
Amidation Activity
L Activity
Linear Activity
Free Activity
Antibacterial Activity
Ceropin A-Magainin 2 Activity
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50=3.4 µM
Anticancer
3.4 µM

Target

Lung Cancer
NCI-H69
Lung

Assay & Model

MTT/MTS assay
72-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1997

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50=3.5 µM
Anticancer
3.5 µM

Target

Lung Cancer
NCI-H128
Lung

Assay & Model

MTT/MTS assay
72-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1997
Evidence 3 Activity

Activity

IC50
IC50=4.5 µM
Anticancer
4.5 µM

Target

Lung Cancer
NCI-H146
Lung

Assay & Model

MTT/MTS assay
72-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1997