Back to search

Peptide record

TPDB15335

P1 Antibacterial Anticancer standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB15335
P1
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
dbAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Anticancer) peptide sequence curated from dbAMP, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
KWKLFKKIGIGAVLKVLKKG-NH2
Physicochemical Analysis
C111H192N28O21
RNDCEQHMPSTY
K
2254.92
11.29
7
0
10
+7
1.65
0.200
131.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
243.91
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
2
I
3
L
7
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 3 K: 7 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
20
C111H192N28O21
2254.92
11.29
+7
1.65
0.200
Amidation
L
Linear
Free
Antibacterial
Ceropin A-Magainin 2
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50=3.4 µM
Anticancer
3.4 µM

Target

Lung Cancer
NCI-H69
Lung

Assay & Model

MTT/MTS assay
72-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1997

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50=3.5 µM
Anticancer
3.5 µM

Target

Lung Cancer
NCI-H128
Lung

Assay & Model

MTT/MTS assay
72-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1997
Evidence 3 Activity

Activity

IC50
IC50=4.5 µM
Anticancer
4.5 µM

Target

Lung Cancer
NCI-H146
Lung

Assay & Model

MTT/MTS assay
72-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1997