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Peptide record

TPDB15334

P3 Antibacterial Anticancer standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB15334
P3
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
dbAMP Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Anticancer) peptide sequence curated from dbAMP, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
KWKLFKKIGIGAFLHSAKKF-NH2
Physicochemical Analysis
C117H183N29O22
RNDCEQMPTYV
K
2347.92
11.21
7
0
10
+6
-0.27
-0.025
88.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
234.25
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
2
I
2
L
6
K
0
M
3
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 2 L: 2 K: 6 M: 0 F: 3 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
20
C117H183N29O22
2347.92
11.21
+6
-0.27
-0.025
Amidation
L
Linear
Free
Antibacterial
Ceropin A-Magainin 2
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50=9.3 µM
Anticancer
9.3 µM

Target

Lung Cancer
NCI-H69
Lung

Assay & Model

MTT/MTS assay
72-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1997

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50=9.3 µM
Anticancer
9.3 µM

Target

Lung Cancer
NCI-H128
Lung

Assay & Model

MTT/MTS assay
72-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1997
Evidence 3 Activity

Activity

IC50
IC50=10.9 µM
Anticancer
10.9 µM

Target

Lung Cancer
NCI-H146
Lung

Assay & Model

MTT/MTS assay
72-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1997