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Peptide record

TPDB15329

Antibacterial Anticancer Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB15329
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
KWKFKKIPKFLHLAKKF
Physicochemical Analysis
C112H175N27O18
RNDCEQGMSTYV
K
2187.79
11.29
8
0
8
+7
1.50
-0.629
74.71
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
251.40
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
2
L
7
K
0
M
3
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 2 K: 7 M: 0 F: 3 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
17
C112H175N27O18
2187.79
11.29
+7
1.50
-0.629
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Toxicity
75 µM
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: hemolysis: 0%=100 µM hemolysis: 0%=50 µM hemolysis: 0%=25.0 µM hemolysis: 0%=12.5 µM hemolysis: 0%=6.25 µM hemolysis: 0%=3.125 µM hemolysis: 0%=1.56 µM hemolysis: 0%=0.78 µM | Cytotoxicity: NIH 3T3: IC50=75 µM

Target

erythrocytes

Source & Reference

NA
DRAMP
J Pept Res. 2001 Dec 58(6):504-14.