Back to search

Peptide record

TPDB15310

Antibacterial Antifungal Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB15310
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia Antifungipept CAFPdb
standard
No
A 14-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KRLFRRWQWRMKKY
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C98H152N32O17S1
ANDCEGHIPSTV
R
2082.55
12.42
7
0
6
+7
4.79
-1.986
27.86
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
12490
6.00
2
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
1
L
3
K
1
M
1
F
0
P
0
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 3 M: 1 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
14 reviewed residue count
C98H152N32O17S1 sequence-only estimate (linear, free termini)
2082.55 sequence-only estimate (linear, free termini)
12.42 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
4.79 sequence-only estimate (linear, free termini)
-1.986 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Fungicidal effect of three new synthetic cationic peptides against Candida albicans. | Oral Dis | 2004