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Peptide record

TPDB15289

[C/U, G1K, L5Y, K8R]cGm Antibacterial Anticancer Antifungal modified_plain modified
18 source-reported length (unverified)
Basic Information
TPDB15289
[C/U, G1K, L5Y, K8R]cGm
Antibacterial Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia CancerPPD 2.0 dbACP dbAMP 3.0 CAFPdb
modified_plain
Yes
A modified multi-activity (Antibacterial, Anticancer, and Antifungal) peptide record curated from dbAMP, DRAMP, Peptipedia, and other sources, without an available 3D structural model. Source-reported length: 18 (unverified).
C-terminal: Cyclized Chemical: U = SelenoCys N-terminal: Cyclized
Sequence
KURRYUYRQRUVTYURGR

Source notation is retained verbatim; residue notation and chemical identity have not been independently validated. The displayed length is source-reported and unverified.

Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
18 source-reported length (unverified)
Cyclized Activity
U = SelenoCys Activity
L Activity
Cyclic Activity
Cyclized Activity
Antimicrobial Activity
Synthetic Analogue of Gomesin Activity
Evidence Records 6 records
Evidence 1 Activity

Activity

CC50
CC50 = 46.2 ± 7.6 µM
Anticancer
46.2

Target

Gastric Cancer
CRL-1739
Stomach

Assay & Model

Resazurin dye assay
24-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP
CancerPPD2
2017

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation. dbAMP 3.0 classified as Anticancer under the disease-associated peptide function classes.
Evidence 2 Activity

Activity

CC50
CC50 = 2.3 ± 0.2 µM
Anticancer
2.3

Target

Skin Cancer
MM96L
Skin

Assay & Model

Resazurin dye assay
24-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP
CancerPPD2
2017
Evidence 3 Activity

Activity

CC50
CC50 = 36.2 ± 2.8 µM
Anticancer
36.2

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

Resazurin dye assay
24-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP
CancerPPD2
2017
Evidence 4 Activity

Activity

CC50
CC50 = 29.0 ± 3.7 µM
Anticancer
29.0

Target

Breast Cancer
MCF-7
Breast

Assay & Model

Resazurin dye assay
24-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP
CancerPPD2
2017
Evidence 5 Activity

Activity

CC50
CC50 = 6.4 ± 0.6 µM
Anticancer
6.4

Target

Leukemia Cancer
K-562
Blood

Assay & Model

Resazurin dye assay
24-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP
CancerPPD2
2017
Evidence 6 Activity

Activity

CC50
CC50 = 33.3 ±7.4µM
Anticancer
33.3

Target

Leukemia Cancer
HL-60
Blood

Assay & Model

Resazurin dye assay
24-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP
CancerPPD2
2017