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Peptide record

TPDB15276

T-Apidaecin Antibacterial Cell-penetrating Peptides modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB15276
T-Apidaecin
Antibacterial Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
dbAMP DRAMP Peptipedia CPPsite3.0
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial and Cell-penetrating Peptides) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Amidation Chemical: O = Ornithine N-terminal: Conjugated with TAMRA
Sequence
ONNRPVYIPRPRPPHPRL-NH2
Physicochemical Analysis
C94H151N33O21
ADCEQGKMFSTW
P
2079.44
12.40
5
0
4
+4
6.00
-1.478
59.44
Mammalian: Yeast: E.coli:
1490
71.65
3
Residue Composition
number
0
A
4
R
2
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
1
L
0
K
0
M
0
F
6
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 1 K: 0 M: 0 F: 0 P: 6 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
18
C94H151N33O21
2079.44
12.40
+4
6.00
-1.478
Amidation
O = Ornithine
Modified
Cationic
Linear
Conjugated with TAMRA
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

bEnd.3 and Bioni-010c cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified Cationic
TAMRA dye and 14C-mannitol
Lesser extent of internalization than T-Tat47–57 and T-penetratin
Endocytosis
In vitro