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Peptide record

TPDB15153

Antibacterial Antifungal standard
80 amino acids
Basic Information
3D PDB MODEL
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TPDB15153
Antibacterial Antifungal
Anti-infective peptides
dbAMP DRAMP Peptipedia Antifp Antifungipept
standard
No
A 80-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
YVDREINLFDHYCIISRSPHISRWELKWQATVTCPGWTPVKGKVRGYSNPLSAEREATRDFVQRIVQRGLVTRDEASEWL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C421H651N123O120S2
M
R
9419.67
8.91
14
10
30
+2
2.42
-0.578
79.12
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
26595
2.82
21
Residue Composition
number
4
A
9
R
2
N
4
D
2
C
6
E
3
Q
4
G
2
H
5
I
5
L
3
K
0
M
2
F
4
P
6
S
5
T
4
W
3
Y
7
V
Amino Acid Distribution
A: 4 R: 9 N: 2 D: 4 C: 2 E: 6 Q: 3 G: 4 H: 2 I: 5 L: 5 K: 3 M: 0 F: 2 P: 4 S: 6 T: 5 W: 4 Y: 3 V: 7
Chemical Descriptors
80 reviewed residue count
C421H651N123O120S2 sequence-only estimate (linear, free termini)
9419.67 sequence-only estimate (linear, free termini)
8.91 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
2.42 sequence-only estimate (linear, free termini)
-0.578 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram-negative bacteria V. alginolyticus and P. aeruginosa ( Liu Y et al., 2012 ).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram-negative bacteria V. alginolyticus and P. aeruginosa ( Liu Y et al., 2012 ).