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Peptide record

TPDB15131

Antibacterial Antifungal standard
95 amino acids
Basic Information
3D PDB MODEL
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TPDB15131
Antibacterial Antifungal
Anti-infective peptides
dbAMP DRAMP Peptipedia AFP-GFuse Antifp Antifungipept CAFPdb
standard
No
A 95-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
YEALVTSILGKLTGLWHNDSVDFMGHICYFRRRPKIRRFKLYHEGKFWCPGWAPFEGRSRTKSRSGSSREATKDFVRKALQNGLVTQQDASLWLN
Physicochemical Analysis
C501H770N148O134S3
R
11106.72
10.56
20
8
35
+9
12.83
-0.622
66.74
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
26595
239.45
24
Residue Composition
number
5
A
10
R
3
N
4
D
2
C
4
E
3
Q
8
G
3
H
3
I
9
L
7
K
1
M
6
F
3
P
8
S
5
T
4
W
3
Y
4
V
Amino Acid Distribution
A: 5 R: 10 N: 3 D: 4 C: 2 E: 4 Q: 3 G: 8 H: 3 I: 3 L: 9 K: 7 M: 1 F: 6 P: 3 S: 8 T: 5 W: 4 Y: 3 V: 4
Chemical Descriptors
95
C501H770N148O134S3
11106.72
10.56
+9
12.83
-0.622
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.29-0.58 µM

Target

V. alginolyticus L59

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
n protein containing this peptide is active against bacteria ( Liu Y et al., 2012 ) Gram- V. alginolyticus L59 (MIC 0.29-0.58 uM), P. aeruginosa P25 (MIC 0.29-0.58 uM), Gram+ M. luteus M2 (MIC 9.26-18.52 uM), S. aureus
Evidence 2 Activity

Activity

MIC
Antibacterial
0.29-0.58 µM

Target

Pseudomonas aeruginosa P25

Source & Reference

dbAMP DRAMP

Other

ve against bacteria ( Liu Y et al., 2012 ) Gram- V. alginolyticus L59 (MIC 0.29-0.58 uM), P. aeruginosa P25 (MIC 0.29-0.58 uM), Gram+ M. luteus M2 (MIC 9.26-18.52 uM), S. aureus S7 (MIC37.04-74.09 uM), and fungus P.
Evidence 3 Activity

Activity

MIC
Antibacterial
9.26-18.52 µM

Target

M. luteus M2

Source & Reference

dbAMP DRAMP

Other

ram- V. alginolyticus L59 (MIC 0.29-0.58 uM), P. aeruginosa P25 (MIC 0.29-0.58 uM), Gram+ M. luteus M2 (MIC 9.26-18.52 uM), S. aureus S7 (MIC37.04-74.09 uM), and fungus P. pastoris GS115 (MIC 4.63-9.26 uM). PtesA
Evidence 4 Activity

Activity

MIC
Antibacterial
37.04-74.09 µM

Target

Staphylococcus aureus S7

Source & Reference

dbAMP DRAMP

Other

9-0.58 uM), P. aeruginosa P25 (MIC 0.29-0.58 uM), Gram+ M. luteus M2 (MIC 9.26-18.52 uM), S. aureus S7 (MIC37.04-74.09 uM), and fungus P. pastoris GS115 (MIC 4.63-9.26 uM). PtesALF2 (PtALF2) has the same amino ac
Evidence 5 Activity

Activity

MIC
Antibacterial
4.63-9.26 µM

Target

P. pastoris GS115

Source & Reference

dbAMP DRAMP

Other

uM), Gram+ M. luteus M2 (MIC 9.26-18.52 uM), S. aureus S7 (MIC37.04-74.09 uM), and fungus P. pastoris GS115 (MIC 4.63-9.26 uM). PtesALF2 (PtALF2) has the same amino acid in the ref.
Evidence 6 Activity

Activity

MIC
Antifungal
0.29-0.58 µM

Target

V. alginolyticus L59

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
n protein containing this peptide is active against bacteria ( Liu Y et al., 2012 ) Gram- V. alginolyticus L59 (MIC 0.29-0.58 uM), P. aeruginosa P25 (MIC 0.29-0.58 uM), Gram+ M. luteus M2 (MIC 9.26-18.52 uM), S. aureus
Evidence 7 Activity

Activity

MIC
Antifungal
0.29-0.58 µM

Target

Pseudomonas aeruginosa P25

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ve against bacteria ( Liu Y et al., 2012 ) Gram- V. alginolyticus L59 (MIC 0.29-0.58 uM), P. aeruginosa P25 (MIC 0.29-0.58 uM), Gram+ M. luteus M2 (MIC 9.26-18.52 uM), S. aureus S7 (MIC37.04-74.09 uM), and fungus P.
Evidence 8 Activity

Activity

MIC
Antifungal
9.26-18.52 µM

Target

M. luteus M2

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ram- V. alginolyticus L59 (MIC 0.29-0.58 uM), P. aeruginosa P25 (MIC 0.29-0.58 uM), Gram+ M. luteus M2 (MIC 9.26-18.52 uM), S. aureus S7 (MIC37.04-74.09 uM), and fungus P. pastoris GS115 (MIC 4.63-9.26 uM). PtesA
Evidence 9 Activity

Activity

MIC
Antifungal
37.04-74.09 µM

Target

Staphylococcus aureus S7

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

9-0.58 uM), P. aeruginosa P25 (MIC 0.29-0.58 uM), Gram+ M. luteus M2 (MIC 9.26-18.52 uM), S. aureus S7 (MIC37.04-74.09 uM), and fungus P. pastoris GS115 (MIC 4.63-9.26 uM). PtesALF2 (PtALF2) has the same amino ac
Evidence 10 Activity

Activity

MIC
Antifungal
4.63-9.26 µM

Target

P. pastoris GS115

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

uM), Gram+ M. luteus M2 (MIC 9.26-18.52 uM), S. aureus S7 (MIC37.04-74.09 uM), and fungus P. pastoris GS115 (MIC 4.63-9.26 uM). PtesALF2 (PtALF2) has the same amino acid in the ref.