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Peptide record

TPDB15130

Antibacterial Antifungal standard
65 amino acids
Basic Information
3D PDB MODEL
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TPDB15130
Antibacterial Antifungal
Anti-infective peptides
dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 65-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
YEALVTSILGKLTGLWHNDSVDFMGHICYFRRRPKIRRFKLYHEGKFWCPGWAPFEGRCKYCVVF
Physicochemical Analysis
C366H538N98O85S5
Q
RGF
7831.20
9.64
14
5
28
+6
2.51
-0.209
68.92
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
22710
289.99
13
Residue Composition
number
2
A
6
R
1
N
2
D
4
C
3
E
0
Q
6
G
3
H
3
I
5
L
5
K
1
M
6
F
3
P
2
S
2
T
3
W
4
Y
4
V
Amino Acid Distribution
A: 2 R: 6 N: 1 D: 2 C: 4 E: 3 Q: 0 G: 6 H: 3 I: 3 L: 5 K: 5 M: 1 F: 6 P: 3 S: 2 T: 2 W: 3 Y: 4 V: 4
Chemical Descriptors
65
C366H538N98O85S5
7831.20
9.64
+6
2.51
-0.209
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.5-1.01 µM

Target

V. alginolyticus L59

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
n protein containing this peptide is active against bacteria ( Liu Y et al., 2012 ) Gram- V. alginolyticus L59 (MIC 0.5-1.01 uM), P. aeruginosa P25 (MIC 1.01-2.01 uM), Gram+ M-luteus M2 (MIC>64.3 uM), S-aureus S7 (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
1.01-2.01 µM

Target

Pseudomonas aeruginosa P25

Source & Reference

dbAMP DRAMP

Other

ive against bacteria ( Liu Y et al., 2012 ) Gram- V. alginolyticus L59 (MIC 0.5-1.01 uM), P. aeruginosa P25 (MIC 1.01-2.01 uM), Gram+ M-luteus M2 (MIC>64.3 uM), S-aureus S7 (MIC >64.3 uM), and fungus P. pastoris GS11
Evidence 3 Activity

Activity

MIC
Antibacterial
8.04-16.08 µM

Target

P. pastoris GS115

Source & Reference

dbAMP DRAMP

Other

IC 1.01-2.01 uM), Gram+ M-luteus M2 (MIC>64.3 uM), S-aureus S7 (MIC >64.3 uM), and fungus P. pastoris GS115 (MIC 8.04-16.08 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
0.5-1.01 µM

Target

V. alginolyticus L59

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
n protein containing this peptide is active against bacteria ( Liu Y et al., 2012 ) Gram- V. alginolyticus L59 (MIC 0.5-1.01 uM), P. aeruginosa P25 (MIC 1.01-2.01 uM), Gram+ M-luteus M2 (MIC>64.3 uM), S-aureus S7 (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
1.01-2.01 µM

Target

Pseudomonas aeruginosa P25

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ive against bacteria ( Liu Y et al., 2012 ) Gram- V. alginolyticus L59 (MIC 0.5-1.01 uM), P. aeruginosa P25 (MIC 1.01-2.01 uM), Gram+ M-luteus M2 (MIC>64.3 uM), S-aureus S7 (MIC >64.3 uM), and fungus P. pastoris GS11
Evidence 6 Activity

Activity

MIC
Antifungal
8.04-16.08 µM

Target

P. pastoris GS115

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

IC 1.01-2.01 uM), Gram+ M-luteus M2 (MIC>64.3 uM), S-aureus S7 (MIC >64.3 uM), and fungus P. pastoris GS115 (MIC 8.04-16.08 uM).