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Peptide record

TPDB15097

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
51 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB15097
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia Antifungipept AVPpred-BWR
standard
No
A 51-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
VTCDLLSFKGQVNDSACAANCLSLGKAGGHCEKVGCICRKTSFKDLWDKRF
Physicochemical Analysis
C237H381N69O71S6
MPY
CK
5525.41
8.31
9
5
17
+3
7.47
-0.086
70.78
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
5875
106.33
15
Residue Composition
number
4
A
2
R
2
N
4
D
6
C
1
E
1
Q
5
G
1
H
1
I
5
L
6
K
0
M
3
F
0
P
4
S
2
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 2 N: 2 D: 4 C: 6 E: 1 Q: 1 G: 5 H: 1 I: 1 L: 5 K: 6 M: 0 F: 3 P: 0 S: 4 T: 2 W: 1 Y: 0 V: 3
Chemical Descriptors
51
C237H381N69O71S6
5525.41
8.31
+3
7.47
-0.086
Evidence Records 36 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6 µg/mL

Target

L. bulgaricus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against G+ bacteria S. aureus, S. thermiphylus, L. bulgaricus (MIC 6 ug/ml) (see AP1210 for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (M
Evidence 2 Activity

Activity

MIC
Antibacterial
7.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

, S. thermiphylus, L. bulgaricus (MIC 6 ug/ml) (see AP1210 for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/m
Evidence 3 Activity

Activity

MIC
Antibacterial
9 µg/mL

Target

S. alactolyticus

Source & Reference

dbAMP DRAMP

Other

ricus (MIC 6 ug/ml) (see AP1210 for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gra
Evidence 4 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

S. intermediusB

Source & Reference

dbAMP DRAMP

Other

for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml)
Evidence 5 Activity

Activity

MIC
Antibacterial
10.5 µg/mL

Target

S. xylosus

Source & Reference

dbAMP DRAMP

Other

S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/m
Evidence 6 Activity

Activity

MIC
Antibacterial
6 µg/mL

Target

P. larvae

Source & Reference

dbAMP DRAMP

Other

alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (
Evidence 7 Activity

Activity

MIC
Antibacterial
10 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP

Other

. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (MIC 4 ug/ml), and E.coli.
Evidence 8 Activity

Activity

MIC
Antibacterial
9 µg/mL

Target

S. cholearasuis

Source & Reference

dbAMP DRAMP

Other

S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (MIC 4 ug/ml), and E.coli.
Evidence 9 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

V. parahaemolyticus

Source & Reference

dbAMP DRAMP

Other

larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (MIC 4 ug/ml), and E.coli.
Evidence 10 Activity

Activity

MIC
Antifungal
6 µg/mL

Target

L. bulgaricus

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against G+ bacteria S. aureus, S. thermiphylus, L. bulgaricus (MIC 6 ug/ml) (see AP1210 for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (M
Evidence 11 Activity

Activity

MIC
Antifungal
7.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP Antifungipept

Other

, S. thermiphylus, L. bulgaricus (MIC 6 ug/ml) (see AP1210 for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/m
Evidence 12 Activity

Activity

MIC
Antifungal
9 µg/mL

Target

S. alactolyticus

Source & Reference

dbAMP DRAMP Antifungipept

Other

ricus (MIC 6 ug/ml) (see AP1210 for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gra
Evidence 13 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

S. intermediusB

Source & Reference

dbAMP DRAMP Antifungipept

Other

for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml)
Evidence 14 Activity

Activity

MIC
Antifungal
10.5 µg/mL

Target

S. xylosus

Source & Reference

dbAMP DRAMP Antifungipept

Other

S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/m
Evidence 15 Activity

Activity

MIC
Antifungal
6 µg/mL

Target

P. larvae

Source & Reference

dbAMP DRAMP Antifungipept

Other

alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (
Evidence 16 Activity

Activity

MIC
Antifungal
10 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP Antifungipept

Other

. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (MIC 4 ug/ml), and E.coli.
Evidence 17 Activity

Activity

MIC
Antifungal
9 µg/mL

Target

S. cholearasuis

Source & Reference

dbAMP DRAMP Antifungipept

Other

S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (MIC 4 ug/ml), and E.coli.
Evidence 18 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

V. parahaemolyticus

Source & Reference

dbAMP DRAMP Antifungipept

Other

larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (MIC 4 ug/ml), and E.coli.
Evidence 19 Activity

Activity

MIC
Antiparasitic
6 µg/mL

Target

L. bulgaricus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against G+ bacteria S. aureus, S. thermiphylus, L. bulgaricus (MIC 6 ug/ml) (see AP1210 for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (M
Evidence 20 Activity

Activity

MIC
Antiparasitic
7.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

, S. thermiphylus, L. bulgaricus (MIC 6 ug/ml) (see AP1210 for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/m
Evidence 21 Activity

Activity

MIC
Antiparasitic
9 µg/mL

Target

S. alactolyticus

Source & Reference

DRAMP

Other

ricus (MIC 6 ug/ml) (see AP1210 for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gra
Evidence 22 Activity

Activity

MIC
Antiparasitic
4 µg/mL

Target

S. intermediusB

Source & Reference

DRAMP

Other

for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml)
Evidence 23 Activity

Activity

MIC
Antiparasitic
10.5 µg/mL

Target

S. xylosus

Source & Reference

DRAMP

Other

S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/m
Evidence 24 Activity

Activity

MIC
Antiparasitic
6 µg/mL

Target

P. larvae

Source & Reference

DRAMP

Other

alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (
Evidence 25 Activity

Activity

MIC
Antiparasitic
10 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (MIC 4 ug/ml), and E.coli.
Evidence 26 Activity

Activity

MIC
Antiparasitic
9 µg/mL

Target

S. cholearasuis

Source & Reference

DRAMP

Other

S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (MIC 4 ug/ml), and E.coli.
Evidence 27 Activity

Activity

MIC
Antiparasitic
4 µg/mL

Target

V. parahaemolyticus

Source & Reference

DRAMP

Other

larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (MIC 4 ug/ml), and E.coli.
Evidence 28 Activity

Activity

MIC
Antiviral
6 µg/mL

Target

L. bulgaricus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against G+ bacteria S. aureus, S. thermiphylus, L. bulgaricus (MIC 6 ug/ml) (see AP1210 for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (M
Evidence 29 Activity

Activity

MIC
Antiviral
7.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

, S. thermiphylus, L. bulgaricus (MIC 6 ug/ml) (see AP1210 for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/m
Evidence 30 Activity

Activity

MIC
Antiviral
9 µg/mL

Target

S. alactolyticus

Source & Reference

DRAMP

Other

ricus (MIC 6 ug/ml) (see AP1210 for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gra
Evidence 31 Activity

Activity

MIC
Antiviral
4 µg/mL

Target

S. intermediusB

Source & Reference

DRAMP

Other

for ref). Also, active against S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml)
Evidence 32 Activity

Activity

MIC
Antiviral
10.5 µg/mL

Target

S. xylosus

Source & Reference

DRAMP

Other

S. aureus (MIC 7.5 ug/ml), S. alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/m
Evidence 33 Activity

Activity

MIC
Antiviral
6 µg/mL

Target

P. larvae

Source & Reference

DRAMP

Other

alactolyticus (MIC 9 ug/ml), S. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (
Evidence 34 Activity

Activity

MIC
Antiviral
10 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

. intermediusB (MIC 4 ug/ml), S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (MIC 4 ug/ml), and E.coli.
Evidence 35 Activity

Activity

MIC
Antiviral
9 µg/mL

Target

S. cholearasuis

Source & Reference

DRAMP

Other

S. xylosus (MIC 10.5 ug/ml), P. larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (MIC 4 ug/ml), and E.coli.
Evidence 36 Activity

Activity

MIC
Antiviral
4 µg/mL

Target

V. parahaemolyticus

Source & Reference

DRAMP

Other

larvae (MIC 6 ug/ml), Gram- P. aeruginosa (MIC 10 ug/ml), S. cholearasuis (MIC 9 ug/ml), V. parahaemolyticus (MIC 4 ug/ml), and E.coli.