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Peptide record

TPDB15092

Antibacterial Antifungal Antiparasitic standard
77 amino acids
Basic Information
3D PDB MODEL
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TPDB15092
Antibacterial Antifungal Antiparasitic
Anti-infective peptides
dbAMP DRAMP Peptipedia AFP-GFuse Antifp Antifungipept CAFPdb dbAMP 3.0 i2APP
standard
No
A 77-aa standard natural multi-activity (Antibacterial, Antifungal, and Antiparasitic) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
VPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP
Physicochemical Analysis
C375H652N114O108S5
DHWY
K
8646.30
10.67
17
6
24
+11
27.10
-0.470
89.87
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
250
2.89
22
Residue Composition
number
4
A
7
R
4
N
0
D
4
C
6
E
2
Q
1
G
0
H
7
I
6
L
10
K
1
M
1
F
7
P
9
S
3
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 4 R: 7 N: 4 D: 0 C: 4 E: 6 Q: 2 G: 1 H: 0 I: 7 L: 6 K: 10 M: 1 F: 1 P: 7 S: 9 T: 3 W: 0 Y: 0 V: 5
Chemical Descriptors
77
C375H652N114O108S5
8646.30
10.67
+11
27.10
-0.470
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
3.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
At 10 ug/ml, it killed 100% E. coli and 77% S. aureus. Active against E. coli (MIC 3.6 ug/ml), P. aeruginosa, L. monocytogenes (MIC 7 ug/ml), S. aureus, and B. anthracis spores and ba
Evidence 2 Activity

Activity

MIC
Antibacterial
7 µg/mL

Target

L. monocytogenes

Source & Reference

dbAMP DRAMP

Other

ed 100% E. coli and 77% S. aureus. Active against E. coli (MIC 3.6 ug/ml), P. aeruginosa, L. monocytogenes (MIC 7 ug/ml), S. aureus, and B. anthracis spores and bacilli(this ref Yang et al., 2003 ). Antifunal:
Evidence 3 Activity

Activity

MIC
Antifungal
3.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
At 10 ug/ml, it killed 100% E. coli and 77% S. aureus. Active against E. coli (MIC 3.6 ug/ml), P. aeruginosa, L. monocytogenes (MIC 7 ug/ml), S. aureus, and B. anthracis spores and ba
Evidence 4 Activity

Activity

MIC
Antifungal
7 µg/mL

Target

L. monocytogenes

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ed 100% E. coli and 77% S. aureus. Active against E. coli (MIC 3.6 ug/ml), P. aeruginosa, L. monocytogenes (MIC 7 ug/ml), S. aureus, and B. anthracis spores and bacilli(this ref Yang et al., 2003 ). Antifunal:
Evidence 5 Activity

Activity

MIC
Antiparasitic
3.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
At 10 ug/ml, it killed 100% E. coli and 77% S. aureus. Active against E. coli (MIC 3.6 ug/ml), P. aeruginosa, L. monocytogenes (MIC 7 ug/ml), S. aureus, and B. anthracis spores and ba
Evidence 6 Activity

Activity

MIC
Antiparasitic
7 µg/mL

Target

L. monocytogenes

Source & Reference

dbAMP 3.0 DRAMP

Other

ed 100% E. coli and 77% S. aureus. Active against E. coli (MIC 3.6 ug/ml), P. aeruginosa, L. monocytogenes (MIC 7 ug/ml), S. aureus, and B. anthracis spores and bacilli(this ref Yang et al., 2003 ). Antifunal: