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Peptide record

TPDB15082

Antibacterial Antifungal standard
87 amino acids
Basic Information
3D PDB MODEL
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TPDB15082
Antibacterial Antifungal
Anti-infective peptides
dbAMP Peptipedia Antifungipept
standard
No
A 87-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
VLEVYYTSLRCRCVQESSVFIPRRFIDRIQILPRGNGCPRKEIIVWKKNKSIVCVDPQAEWIQRMMEVLRKRSSSTLPVPVFKRKIP
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C463H763N135O119S6
H
R
10317.34
10.70
18
7
34
+11
2.10
-0.232
97.24
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
14230
1.38
21
Residue Composition
number
1
A
11
R
2
N
2
D
4
C
5
E
4
Q
2
G
0
H
9
I
5
L
7
K
2
M
3
F
7
P
7
S
2
T
2
W
2
Y
10
V
Amino Acid Distribution
A: 1 R: 11 N: 2 D: 2 C: 4 E: 5 Q: 4 G: 2 H: 0 I: 9 L: 5 K: 7 M: 2 F: 3 P: 7 S: 7 T: 2 W: 2 Y: 2 V: 10
Chemical Descriptors
87 reviewed residue count
C463H763N135O119S6 sequence-only estimate (linear, free termini)
10317.34 sequence-only estimate (linear, free termini)
10.70 sequence-only estimate (linear, free termini)
+11 sequence-only estimate (linear, free termini)
2.10 sequence-only estimate (linear, free termini)
-0.232 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
At 10 ug/ml, it killed 83% E. coli and 50% S. aureus. Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
At 10 ug/ml, it killed 83% E. coli and 50% S. aureus. Updated 7/2021