TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB15077

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 125-aa standard natural antibacterial peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.

Sequence

VKGGKEKWGNCPAEKGSCIKSGPSQCHADNDCPGDKKCCFLSCSFKCVSPDRIRKEGGNEDEDVSRSSPEPGGEPRPPGSSPSTSILSYYAVSFPPPGIGQMAPVPQGAESWNVGQEASPQKEWS

FASTA

>TPDB15077|Antibacterial|length=125
VKGGKEKWGNCPAEKGSCIKSGPSQCHADNDCPGDKKCCFLSCSFKCVSPDRIRKEGGNEDEDVSRSSPEPGGEPRPPGSSPSTSILSYYAVSFPPPGIGQMAPVPQGAESWNVGQEASPQKEWS

Formula C564H869N161O188S9

Absent Amino Acids

Common Amino Acids S

Mass 13201.61

PI 5.25

Basic Residues 15

Acidic Residues 16

Hydrophobic Residues 27

Net Charge -2

Boman Index 40.16

Hydrophobicity -0.862

Aliphatic Index 37.44

Half Life

Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 19980

Absorbance 280nm 151.35

Polar Residues 38

number

6

A

4

R

4

N

6

D

8

C

10

E

5

Q

15

G

1

H

4

I

2

L

10

K

1

M

3

F

16

P

18

S

1

T

3

W

2

Y

6

V

Amino Acid Distribution

A: 6 R: 4 N: 4 D: 6 C: 8 E: 10 Q: 5 G: 15 H: 1 I: 4 L: 2 K: 10 M: 1 F: 3 P: 16 S: 18 T: 1 W: 3 Y: 2 V: 6

Length

125

Formula

C564H869N161O188S9

Mass

13201.61

PI

5.25

Net Charge

-2

Boman Index

40.16

Hydrophobicity

-0.862

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.