Peptide record

TPDB15053

Antibacterial Antifungal standard
6 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB15053
Antibacterial Antifungal
Anti-infective peptides
dbAMP DRAMP Peptipedia CAFPdb
standard
No
A 6-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
TVVTQA
Physicochemical Analysis
C26H47N7O10
RNDCEGHILKMFPSWY
TV
617.70
6.02
0
0
3
-0
0.83
0.883
113.33
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
6
C26H47N7O10
617.70
6.02
-0
0.83
0.883
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.56-6.25 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
is active against Gram-positive S. aureus FDA 209p, S. aureus Smith, M. luteus IFO 3333, B. subtilis ATCC 6633 (MIC 1.56-6.25 ug/ml), and fungi F. oxysporum HF8801, F. oxysporum HF8835, A. niger HUT 2016, A. oryzae 1FO 421
Evidence 2 Activity

Activity

MIC
Antibacterial
1.56-3.12 µg/mL

Target

P. thomii

Source & Reference

dbAMP DRAMP

Other

nd fungi F. oxysporum HF8801, F. oxysporum HF8835, A. niger HUT 2016, A. oryzae 1FO 4214, P. thomii (MIC 1.56-3.12 ug/ml), C. albicans IFO 1594, S. cerevisiae HUT 7099 (MIC 12.5 ug/ml). Inactive: E.coli NIHJ, K.
Evidence 3 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

S. cerevisiae HUT 7099

Source & Reference

dbAMP DRAMP

Other

iger HUT 2016, A. oryzae 1FO 4214, P. thomii (MIC 1.56-3.12 ug/ml), C. albicans IFO 1594, S. cerevisiae HUT 7099 (MIC 12.5 ug/ml). Inactive: E.coli NIHJ, K.pneumoniae KC-1, P.aeruginosa IFO 3445, S.marcescens IFO 3736 (
Evidence 4 Activity

Activity

MIC
Antifungal
1.56-6.25 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP DRAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
is active against Gram-positive S. aureus FDA 209p, S. aureus Smith, M. luteus IFO 3333, B. subtilis ATCC 6633 (MIC 1.56-6.25 ug/ml), and fungi F. oxysporum HF8801, F. oxysporum HF8835, A. niger HUT 2016, A. oryzae 1FO 421
Evidence 5 Activity

Activity

MIC
Antifungal
1.56-3.12 µg/mL

Target

P. thomii

Source & Reference

dbAMP DRAMP CAFPdb

Other

nd fungi F. oxysporum HF8801, F. oxysporum HF8835, A. niger HUT 2016, A. oryzae 1FO 4214, P. thomii (MIC 1.56-3.12 ug/ml), C. albicans IFO 1594, S. cerevisiae HUT 7099 (MIC 12.5 ug/ml). Inactive: E.coli NIHJ, K.
Evidence 6 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

S. cerevisiae HUT 7099

Source & Reference

dbAMP DRAMP CAFPdb

Other

iger HUT 2016, A. oryzae 1FO 4214, P. thomii (MIC 1.56-3.12 ug/ml), C. albicans IFO 1594, S. cerevisiae HUT 7099 (MIC 12.5 ug/ml). Inactive: E.coli NIHJ, K.pneumoniae KC-1, P.aeruginosa IFO 3445, S.marcescens IFO 3736 (