Peptide record

TPDB15050

Antibacterial Antifungal Antiparasitic standard
103 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB15050
Antibacterial Antifungal Antiparasitic
Anti-infective peptides
dbAMP Peptipedia Antifungipept dbAMP 3.0 i2APP
standard
No
A 103-aa standard natural multi-activity (Antibacterial, Antifungal, and Antiparasitic) peptide sequence curated from dbAMP, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
TPVVRKGRCSCISTNQGTIHLQSLKDLKQFAPSPSCEKIEIIATLKNGVQTCLNPDSADVKELIKKWEKQVSQKKKQKNGKKHQKKKVLKVRKSQRSRQKKTT
Physicochemical Analysis
C509H881N159O148S4
MY
K
11724.81
10.83
29
7
25
+20
41.25
-1.049
71.84
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
5750
49.04
34
Residue Composition
number
3
A
5
R
4
N
3
D
4
C
4
E
10
Q
4
G
2
H
6
I
7
L
22
K
0
M
1
F
4
P
9
S
7
T
1
W
0
Y
7
V
Amino Acid Distribution
A: 3 R: 5 N: 4 D: 3 C: 4 E: 4 Q: 10 G: 4 H: 2 I: 6 L: 7 K: 22 M: 0 F: 1 P: 4 S: 9 T: 7 W: 1 Y: 0 V: 7
Chemical Descriptors
103
C509H881N159O148S4
11724.81
10.83
+20
41.25
-1.049
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.5 µg/mL

Target

Escherichia coli ML-35p

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
At 10 ug/ml, it killed 100% E. coli and 81% S. aureus. Also active against E. coli ML-35p (MIC 0.5 ug/ml) and L. monocytogenes (MIC 3.6 ug/ml). Antimicrobial activity was also established by ( Ya
Evidence 2 Activity

Activity

MIC
Antibacterial
3.6 µg/mL

Target

L. monocytogenes

Source & Reference

dbAMP

Other

ed 100% E. coli and 81% S. aureus. Also active against E. coli ML-35p (MIC 0.5 ug/ml) and L. monocytogenes (MIC 3.6 ug/ml). Antimicrobial activity was also established by ( Yang et al., 2003 ) against E. coli ~ S
Evidence 3 Activity

Activity

MIC
Antifungal
0.5 µg/mL

Target

Escherichia coli ML-35p

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
At 10 ug/ml, it killed 100% E. coli and 81% S. aureus. Also active against E. coli ML-35p (MIC 0.5 ug/ml) and L. monocytogenes (MIC 3.6 ug/ml). Antimicrobial activity was also established by ( Ya
Evidence 4 Activity

Activity

MIC
Antifungal
3.6 µg/mL

Target

L. monocytogenes

Source & Reference

dbAMP Antifungipept

Other

ed 100% E. coli and 81% S. aureus. Also active against E. coli ML-35p (MIC 0.5 ug/ml) and L. monocytogenes (MIC 3.6 ug/ml). Antimicrobial activity was also established by ( Yang et al., 2003 ) against E. coli ~ S
Evidence 5 Activity

Activity

MIC
Antiparasitic
0.5 µg/mL

Target

Escherichia coli ML-35p

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
At 10 ug/ml, it killed 100% E. coli and 81% S. aureus. Also active against E. coli ML-35p (MIC 0.5 ug/ml) and L. monocytogenes (MIC 3.6 ug/ml). Antimicrobial activity was also established by ( Ya
Evidence 6 Activity

Activity

MIC
Antiparasitic
3.6 µg/mL

Target

L. monocytogenes

Source & Reference

dbAMP 3.0

Other

ed 100% E. coli and 81% S. aureus. Also active against E. coli ML-35p (MIC 0.5 ug/ml) and L. monocytogenes (MIC 3.6 ug/ml). Antimicrobial activity was also established by ( Yang et al., 2003 ) against E. coli ~ S