Back to search

Peptide record

TPDB15045

Antibacterial standard
91 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB15045
Antibacterial
Anti-infective peptides
dbAMP Peptipedia
standard
No
A 91-aa standard natural antibacterial peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
TKLEEHLEGIVNIFHQYSVRKGHFDTLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISLVAIALKAAHYHTHKE
Physicochemical Analysis
C471H744N126O142
CMPW
LK
10443.85
5.80
17
15
37
-3
31.87
-0.425
100.77
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
2980
28.53
20
Residue Composition
number
7
A
1
R
4
N
6
D
0
C
9
E
6
Q
4
G
6
H
8
I
10
L
10
K
0
M
5
F
0
P
3
S
5
T
0
W
2
Y
5
V
Amino Acid Distribution
A: 7 R: 1 N: 4 D: 6 C: 0 E: 9 Q: 6 G: 4 H: 6 I: 8 L: 10 K: 10 M: 0 F: 5 P: 0 S: 3 T: 5 W: 0 Y: 2 V: 5
Chemical Descriptors
91
C471H744N126O142
10443.85
5.80
-3
31.87
-0.425
Evidence Records 1 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against H. pylori. 750 ug/ml S100A12 protein, H. pylori growth was repressed by 40% and viability was decreased 1.5 log units. In addition, it inhibited (83%) S. pneumoniae at 250 ug/ml (23.9 uM) ( Mishra et al., 2024 ), and Mycobaterium spp., S. aureus, and C. jejuni . It also inhibitedbiofilm formation:bacteria:P. aeruginosa ( Mishra et al., 2022 ).