TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB15041

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 138-aa standard natural antibacterial peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.

Sequence

TDTGKKDKQEKKVKKSDCGDWQWSVCVPTSGDCGLGTREGTRSGKECKQTIKTQKCKIPCNWKKQFGAECKYQFQEWGDCDPETGLKTRNGNLKRALHNAECQKTVTLSKPCGKVTKPKLQESKKKKKEGKNKEKLLD

FASTA

>TPDB15041|Antibacterial|length=138
TDTGKKDKQEKKVKKSDCGDWQWSVCVPTSGDCGLGTREGTRSGKECKQTIKTQKCKIPCNWKKQFGAECKYQFQEWGDCDPETGLKTRNGNLKRALHNAECQKTVTLSKPCGKVTKPKLQESKKKKKEGKNKEKLLD

Formula C669H1104N200O208S10

Absent Amino Acids M

Common Amino Acids K

Mass 15597.94

PI 9.84

Basic Residues 35

Acidic Residues 18

Hydrophobic Residues 25

Net Charge +16

Boman Index 57.84

Hydrophobicity -1.341

Aliphatic Index 40.94

Half Life

Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 24115

Absorbance 280nm 154.60

Polar Residues 43

number

3

A

4

R

5

N

8

D

10

C

10

E

9

Q

13

G

1

H

2

I

8

L

30

K

0

M

2

F

5

P

6

S

12

T

4

W

1

Y

5

V

Amino Acid Distribution

A: 3 R: 4 N: 5 D: 8 C: 10 E: 10 Q: 9 G: 13 H: 1 I: 2 L: 8 K: 30 M: 0 F: 2 P: 5 S: 6 T: 12 W: 4 Y: 1 V: 5

Length

138

Formula

C669H1104N200O208S10

Mass

15597.94

PI

9.84

Net Charge

+16

Boman Index

57.84

Hydrophobicity

-1.341

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.