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Peptide record

TPDB15036

Antibacterial Antifungal standard
104 amino acids
Basic Information
3D PDB MODEL
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TPDB15036
Antibacterial Antifungal
Anti-infective peptides
dbAMP Peptipedia Antifungipept CAFPdb
standard
No
A 104-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
TDHQMAQSACIGVSQDNAYASAIPRDCHGGKTCEGICADATATMDRYSDTGGPLSIARCVNAFHFYKRRGEENVSYKPFVVSWKYGVAGCFYTHCGPNFCCCIS
Physicochemical Analysis
C485H729N139O150S12
A
11291.69
6.95
13
9
37
-0
12.93
-0.216
49.81
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
15065
133.42
37
Residue Composition
number
11
A
5
R
4
N
6
D
10
C
3
E
3
Q
10
G
4
H
5
I
1
L
4
K
2
M
5
F
4
P
8
S
6
T
1
W
6
Y
6
V
Amino Acid Distribution
A: 11 R: 5 N: 4 D: 6 C: 10 E: 3 Q: 3 G: 10 H: 4 I: 5 L: 1 K: 4 M: 2 F: 5 P: 4 S: 8 T: 6 W: 1 Y: 6 V: 6
Chemical Descriptors
104
C485H729N139O150S12
11291.69
6.95
-0
12.93
-0.216
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.7-12.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against Gram- E. coli (MIC 6.7-12.5 ug/ml) V. harveyi (12.5-25 ug/ml) Gram+ B. subtilis, S. luteus (1.2-2.5 ug/ml) S. aureus and
Evidence 2 Activity

Activity

MIC
Antibacterial
6.7-12.5 µg/mL

Target

Candida albicans

Source & Reference

dbAMP

Other

. subtilis, S. luteus (1.2-2.5 ug/ml) S. aureus and B. magaterium (2.5-5.0 ug/ml) fungi C. albicans (MIC 6.7-12.5 ug/ml), and M. albicans (12.5-25 ug/ml). Updated 8/2017 GW.
Evidence 3 Activity

Activity

MIC
Antifungal
6.7-12.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against Gram- E. coli (MIC 6.7-12.5 ug/ml) V. harveyi (12.5-25 ug/ml) Gram+ B. subtilis, S. luteus (1.2-2.5 ug/ml) S. aureus and
Evidence 4 Activity

Activity

MIC
Antifungal
6.7-12.5 µg/mL

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

. subtilis, S. luteus (1.2-2.5 ug/ml) S. aureus and B. magaterium (2.5-5.0 ug/ml) fungi C. albicans (MIC 6.7-12.5 ug/ml), and M. albicans (12.5-25 ug/ml). Updated 8/2017 GW.