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Peptide record

TPDB15032

Antibacterial Anticancer Antifungal Antiparasitic standard
79 amino acids
Basic Information
3D PDB MODEL
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TPDB15032
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 79-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
SYFSAWAGPGCNNHNARYSKCGCSNIGHNVHGGYEFVYQGQTAAAYNTDNCKGVAQTRFSSSVNQACSNFGWKSVFIQC
Physicochemical Analysis
C371H536N110O115S6
LM
NGS
8569.36
8.29
8
2
27
+3
2.41
-0.452
38.35
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
18825
219.68
37
Residue Composition
number
8
A
2
R
9
N
1
D
6
C
1
E
5
Q
9
G
3
H
2
I
0
L
3
K
0
M
5
F
1
P
9
S
3
T
2
W
5
Y
5
V
Amino Acid Distribution
A: 8 R: 2 N: 9 D: 1 C: 6 E: 1 Q: 5 G: 9 H: 3 I: 2 L: 0 K: 3 M: 0 F: 5 P: 1 S: 9 T: 3 W: 2 Y: 5 V: 5
Chemical Descriptors
79
C371H536N110O115S6
8569.36
8.29
+3
2.41
-0.452
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Application of Pm-AMP1 resulted in visible hyphal growth inhibition of C. ribicola, P. sulphurascens, O. montium, and O. clavigerum 3-12 days post-treatment. Pm-AMP1 also inhibited spore germination of several other phytopathogenic fungi by 32%-84% 5 days post-treatment ( Can J Microbiol. 2011 ). It confers resistance to multiple fungal pathogens in canola (Brassica napus) ( Plant Mol Biol. 2012 ). Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Application of Pm-AMP1 resulted in visible hyphal growth inhibition of C. ribicola, P. sulphurascens, O. montium, and O. clavigerum 3-12 days post-treatment. Pm-AMP1 also inhibited spore germination of several other phytopathogenic fungi by 32%-84% 5 days post-treatment ( Can J Microbiol. 2011 ). It confers resistance to multiple fungal pathogens in canola (Brassica napus) ( Plant Mol Biol. 2012 ). Updated 7/2021
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Application of Pm-AMP1 resulted in visible hyphal growth inhibition of C. ribicola, P. sulphurascens, O. montium, and O. clavigerum 3-12 days post-treatment. Pm-AMP1 also inhibited spore germination of several other phytopathogenic fungi by 32%-84% 5 days post-treatment ( Can J Microbiol. 2011 ). It confers resistance to multiple fungal pathogens in canola (Brassica napus) ( Plant Mol Biol. 2012 ). Updated 7/2021