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Peptide record

TPDB15027

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
84 amino acids
Basic Information
3D PDB MODEL
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TPDB15027
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia Antifungipept AVPpred-BWR APD_complete APD_hemolytic
standard
No
A 84-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
SVIGCEICEWLVATAEGFVNKTKPQIEQELLQICAKLGPYEQICDQLVLMELPDIIDQIIAKEPPAIVCSQVKICNGSAMAVAA
Physicochemical Analysis
C402H659N99O122S8
RH
I
9087.72
4.07
5
11
39
-6
18.47
0.455
118.45
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
7365
81.04
21
Residue Composition
number
9
A
0
R
2
N
3
D
6
C
8
E
7
Q
4
G
0
H
11
I
7
L
5
K
2
M
1
F
5
P
3
S
2
T
1
W
1
Y
7
V
Amino Acid Distribution
A: 9 R: 0 N: 2 D: 3 C: 6 E: 8 Q: 7 G: 4 H: 0 I: 11 L: 7 K: 5 M: 2 F: 1 P: 5 S: 3 T: 2 W: 1 Y: 1 V: 7
Chemical Descriptors
84
C402H659N99O122S8
9087.72
4.07
-6
18.47
0.455
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
no activity against B-subtilis (MIC >10 uM) and E-coli D31 (MIC >10 uM). naegleriapore B possesses two sugar moieties. has pore-forming activity in liposomes.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
no activity against B-subtilis (MIC >10 uM) and E-coli D31 (MIC >10 uM). naegleriapore B possesses two sugar moieties. has pore-forming activity in liposomes.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

NA

Other

no activity against B-subtilis (MIC >10 uM) and E-coli D31 (MIC >10 uM). naegleriapore B possesses two sugar moieties. has pore-forming activity in liposomes.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

NA

Other

no activity against B-subtilis (MIC >10 uM) and E-coli D31 (MIC >10 uM). naegleriapore B possesses two sugar moieties. has pore-forming activity in liposomes.
Evidence 5 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.