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Peptide record

TPDB15024

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
82 amino acids
Basic Information
3D PDB MODEL
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TPDB15024
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 82-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
SSFSPPRGPPGWGPPCVQQPCPKCPYDDYKCPTCDKFPECEECPHISIGCECGYFSCECPKPVCEPCESPIAELIKKGGYKG
Physicochemical Analysis
C390H581N97O118S13
NM
P
8933.26
4.80
9
11
16
-3
23.96
-0.585
32.07
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
12210
136.68
26
Residue Composition
number
1
A
1
R
0
N
3
D
13
C
8
E
2
Q
8
G
1
H
4
I
1
L
7
K
0
M
3
F
16
P
6
S
1
T
1
W
4
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 3 C: 13 E: 8 Q: 2 G: 8 H: 1 I: 4 L: 1 K: 7 M: 0 F: 3 P: 16 S: 6 T: 1 W: 1 Y: 4 V: 2
Chemical Descriptors
82
C390H581N97O118S13
8933.26
4.80
-3
23.96
-0.585
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
This peptide showed weak activity (MIC 40-80 uM) against Gram- bacteria such as Vibrio splendidus LGP132, V. penaecidae, V. nigripulchritudo , and strong activity against pathogenic fungus Fusarium oxysporum (MIC 2.5 uM). In vitro test showed that it agglutinates bacteria (bacteria-agglutinating) and also binds LPS.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
This peptide showed weak activity (MIC 40-80 uM) against Gram- bacteria such as Vibrio splendidus LGP132, V. penaecidae, V. nigripulchritudo , and strong activity against pathogenic fungus Fusarium oxysporum (MIC 2.5 uM). In vitro test showed that it agglutinates bacteria (bacteria-agglutinating) and also binds LPS.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

NA

Other

This peptide showed weak activity (MIC 40-80 uM) against Gram- bacteria such as Vibrio splendidus LGP132, V. penaecidae, V. nigripulchritudo , and strong activity against pathogenic fungus Fusarium oxysporum (MIC 2.5 uM). In vitro test showed that it agglutinates bacteria (bacteria-agglutinating) and also binds LPS.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

NA

Other

This peptide showed weak activity (MIC 40-80 uM) against Gram- bacteria such as Vibrio splendidus LGP132, V. penaecidae, V. nigripulchritudo , and strong activity against pathogenic fungus Fusarium oxysporum (MIC 2.5 uM). In vitro test showed that it agglutinates bacteria (bacteria-agglutinating) and also binds LPS.