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Peptide record

TPDB15020

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
84 amino acids
Basic Information
3D PDB MODEL
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TPDB15020
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP DRAMP Peptipedia ACP740 _ACP240 dbACP AFP-GFuse Antifungipept CAFPdb dbAMP 3.0
standard
No
A 84-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
SQLGDLGSGAGQGGGGGGSIRAAGGAFGKLEAAREEEFFYKKQKEQLERLKNDQIHQAEFHHQQIKEHEEAIQRHKDFLNNLHK
Physicochemical Analysis
C406H632N128O127
CMPTWV
G
9338.27
6.72
18
13
25
-0
34.70
-1.093
60.60
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
1490
15.96
16
Residue Composition
number
8
A
4
R
3
N
3
D
0
C
10
E
9
Q
13
G
6
H
4
I
7
L
8
K
0
M
5
F
0
P
3
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 8 R: 4 N: 3 D: 3 C: 0 E: 10 Q: 9 G: 13 H: 6 I: 4 L: 7 K: 8 M: 0 F: 5 P: 0 S: 3 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
84
C406H632N128O127
9338.27
6.72
-0
34.70
-1.093
Evidence Records 9 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
It showed no activity against G- bacteria nor fungi tested.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
It showed no activity against G- bacteria nor fungi tested.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
It showed no activity against G- bacteria nor fungi tested.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
It showed no activity against G- bacteria nor fungi tested.
Evidence 5 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Isolation, characterization and anti-cancer activity of SK84, a novel glycine-rich antimicrobial peptide from Drosophila virilis. | Peptides | 2010
Evidence 6 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Chinese hamster ovary cells CHO

Target

Chinese hamster ovary cells CHO

Source & Reference

NA
DBAASP
Isolation, characterization and anti-cancer activity of SK84, a novel glycine-rich antimicrobial peptide from Drosophila virilis. | Peptides | 2010
Evidence 7 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Isolation, characterization and anti-cancer activity of SK84, a novel glycine-rich antimicrobial peptide from Drosophila virilis. | Peptides | 2010
Evidence 8 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Isolation, characterization and anti-cancer activity of SK84, a novel glycine-rich antimicrobial peptide from Drosophila virilis. | Peptides | 2010
Evidence 9 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.19799950]0.01% hemolytic activity at 100 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2010 Jan 31(1):44-50.