TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB15014

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 122-aa standard natural antibacterial peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.

Sequence

SLVELGKMILQETGKNPLTSYGAYGCNCGVGGRGKPKDATDRCCYVHKCCYKKMTDCDPKKDRYSYSWKDKTIVCGEKNSCLKELCECDKAVAICLRENLDTYNKKYKNNYLKPFCKKADAC

FASTA

>TPDB15014|Antibacterial|length=122
SLVELGKMILQETGKNPLTSYGAYGCNCGVGGRGKPKDATDRCCYVHKCCYKKMTDCDPKKDRYSYSWKDKTIVCGEKNSCLKELCECDKAVAICLRENLDTYNKKYKNNYLKPFCKKADAC

Formula C594H951N165O181S16

Absent Amino Acids

Common Amino Acids K

Mass 13813.04

PI 8.52

Basic Residues 25

Acidic Residues 15

Hydrophobic Residues 36

Net Charge +8

Boman Index 32.19

Hydrophobicity -0.733

Aliphatic Index 55.16

Half Life

Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 19785

Absorbance 280nm 143.23

Polar Residues 42

number

6

A

4

R

7

N

9

D

14

C

6

E

1

Q

9

G

1

H

3

I

9

L

20

K

2

M

1

F

4

P

5

S

6

T

1

W

9

Y

5

V

Amino Acid Distribution

A: 6 R: 4 N: 7 D: 9 C: 14 E: 6 Q: 1 G: 9 H: 1 I: 3 L: 9 K: 20 M: 2 F: 1 P: 4 S: 5 T: 6 W: 1 Y: 9 V: 5

Length

122

Formula

C594H951N165O181S16

Mass

13813.04

PI

8.52

Net Charge

+8

Boman Index

32.19

Hydrophobicity

-0.733

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.